Effect of Fluocinolone-N treatment on fetal liver development in White Wistar Rats

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DOI:

https://doi.org/10.24193/subbbiol.2019.2.07

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©2019 Studia Universitatis Babeș-Bolyai Biologia This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Abstract

Exposure to synthetic glucocorticoids during development can result in later cardiovascular and renal disease in sheep and rats. Although prenatal glucocorticoid exposure is associated with impaired renal development, less is known about effects on the developing liver. The main objective of this study is to analyze the side effects of glucocorticoid excess when treatment is done with Fluocinolone-N ointment, to see if it has any effect on rat newborns liver which have an important role in development of fetuses. Our results demonstrate that Fluocinolone-N treatment has negative impact upon the embryologic development of liver.

Author Biography

Erika KIS, Babeș-Bolyai University, Cluj-Napoca, Romania. E-mail: kiserika2001@yahoo.com

Babeș-Bolyai University, Department of Biology-Geology, Cluj-Napoca, Romania. E-mail: kiserika2001@yahoo.com

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Published

2019-12-10

How to Cite

KIS, E. (2019). Effect of Fluocinolone-N treatment on fetal liver development in White Wistar Rats. Studia Universitatis Babeș-Bolyai Biologia, 64(2), 83–95. https://doi.org/10.24193/subbbiol.2019.2.07

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